The company is specialized in the design, production and installation of pharmaceutical machinery, dairy/beverage &food machinery, chemical industry machinery and sanitary fluid equipments etc. We are the leading professional machinery and equipment supplier; we produced the equipment with a long history of over 15 years in China.
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Bioreactor Fermentation Tank
Suitable for
Microbiology fermentation&culture ,vaccine
Volume capacity
10L-10000L
Jacket heating medium
Steam,electrical ,hot water
Jacket cooling medium
Chiller ,cooling water
Mixer type :
Top propeller agitator.
Control system :
PLC automatic contro
Fittings in the tank
Manhole ,vent filter ,level senosr ,PH sensor,PO2 Sensor ,foam sensor ,temperature sensor ,pressure sensor ,safety valve,sampling valve.
Warranty: 1-Year
What is fermentor bio-reactor
Fermentor reactor is used for various kinds of microbiology fermentation ,our equipment adopt the top mechanical agitator system ,the speed can adjustable ,and the all parameters can control ,like the reactor temperature ,pressure PH data ,PO2 data ,foam destroyed etc .all the parameters can be recorded ,stored and printed from the control panel automatic .so it is excellent stability and convenient operation .
Fermentor bioreactor configuration
Body configuration: stainless steel SUS316L / SUS304 material; jacket temperature control, optimized diversion design; internal surface polishing, RA ≤ 0.4 μm; external surface polishing or matte treatment; large angle long strip mirror, pH electrode, do electrode, temperature electrode interface are complete; tank cover is equipped with flame inoculation port and feeding standby interface, etc.
Mixing system: top type mechanical mixing system; aseptic mechanical sealing system; DC mixing motor or AC motor; standard 2-layer flat impeller, one-stage high-efficiency defoaming paddle; optional inclined blade, curved blade, axial flow paddle, etc.; adjustable speed, digital set speed control.
Structural mode: floor type frame structure, saving space and convenient operation.
Ventilation system: deep ventilation, all stainless steel pipeline; glass rotameter display, pressure gauge display, manual valve to regulate the flow; German sartorius high-efficiency sterilization filter with stainless steel shell, filtering accuracy 0.01 μ m; external compressed air is required, equipped with high-quality water removal and pressure stabilizing device, to continuously and stably supply gas; optional mass flow controller to automatically control the air flow.
Tank pressure control: the top exhaust port is equipped with pointer type pressure gauge to display the tank pressure, and the stainless steel valve is manually adjusted; the optional inlet pressure transmitter and automatic regulating valve are equipped to realize automatic tank pressure control.
Temperature control: online detection, digital setting, automatic / manual control free switching; PT-100 temperature probe; electric heating temperature control and external cooling water automatic temperature control.
PH control: online detection, 2-way peristaltic pump automatically flows alkali or acid solution for adjustment; imported pH electrode can be sterilized by high temperature steam.
Dissolved oxygen (do): online detection, range 0-100% or 0-200%; imported do electrode, which can be sterilized by high temperature steam; it can be controlled in linkage with speed and ventilation.
Replenishment control: Standard 1-way peristaltic pump time proportional flow replenishment, flow replenishment cumulative display and record.
Defoaming mode: conductive foam electrode, automatic alarm for abnormal foam condition; standard 1 way peristaltic pump automatic / manual flow adding defoamer, cumulative volume display and record.
Control system: Siemens PLC controller real color plus touch screen, complete functions, stable operation.
Sterilization mode: in place sterilization, manual control.
Fermentor bioreactor Advantages
In place sterilization, safe and reliable, no transmission leakage risk; large viewing angle longitudinal mirror observation is clear; inoculation methods are various and reliable (standard flame inoculation port, differential pressure inoculation port and other forms are optional); floor type tank is beautiful and generous; operation and disassembly are easy; special specifications can be customized.
Fermentation tank：three layers ,inside shell,material isSS316L,jacket material is SS304 ,outside with insulation layer cladding 2mm SS304 Sheet .top mounted propeller type agitator ( and foam destroyer ) ,.with the fittings of aspetic sampling valve ,bottom flush valve ,sight glass ,sight light ,PT sensor,pressure sensor,safety valve ,PH sensor ,DO sensor ,foam sensor ,level sensor,CIP spray ball ,SIP nozzle ,air purge etc ,seed culture and harvest system etc . contact product product material is SS316L ,non-contact part is SS304 ,inside mirror polish is Ra<0.4um ,outside surface polish is Ra<0.6um.
Air filter：single stage filter ,filter micropore is 0.01μm,can online SIP .
Temperature PID control：use the steam to heating and chiller to recycle cooling to make the temperature PID control .
Flow meter：use the electronic flow meter to control the inlet air online
Sampling valve：SS316L material, aspetic type ,can be sterilizer online
PH data control：With intelligent PID control, the pH control performance is very good. It is equipped with special pH electrode for fermentation. The control range is 2-12ph, the display range is 0-14ph, the control precision is ± 0.02PH, and the resolution is 0.01ph；
P02 data control：With the intelligent PID control, The system is equipped with special do electrode for fermentation, control range: 0-100%, display range: 0-200%, control precision: ± 5%, resolution: 0.1%;
SIP system：It has perfect and reliable tank sterilization system, sterilization temperature: 100-130 ℃;
we use the peristaltic pumps to feed the raw material ,acid ,alkali ,foam destroyer solution etc. feeding volume can be measured;Specially designed feeding needle is equipped to ensure safe operation of feeding.
Control system
1.PLC/HMI:he analysis and control system of biological fermentation process is composed of field controller (special software + Siemens PLC-S7200 ,HMI is Siemens-TP1200), sensors and actuators.Features of control system: the field controller is based on S7-200 series programmable controller of Siemens as the core and special software. It adopts multi-level expansion, strong function, safety and stability, and is easy to maintain and upgrade. The industrial Siemens man-machine interface is adopted in the field controller The intelligent PID control is adopted in the control aspect, which has stable control, high control precision and parameter self-tuning control algorithm.
2.Detection and control function:At the same time, it can detect and control the mixing speed, temperature the tank, pH value, DO2 value, feeding, acid and alkali, defoaming, etc;
3.PID regulation:Each parameter has PID adjustment process display, such as set val real-time value, PID set value, upper and lower limit value;
4.alarm function:it can set the upper and lower limits of temperature, speed, pH value and
DO2 value, and has the function of over limit alarm;
5.Control switching:The speed, temperature, pH value, DO2 value and feeding can be set to automatic or manual ;
6.Timing and quantitative feeding:There is a perfect feeding system, the peristaltic pump can be fixed time and quantitative feeding, feeding can be measured, can be displayed in curve;
7.Defoaming and rehydration:It has the function of over liquid level alarm and automatic liqu replenishment, and has the function of over foam alarm and automat addition of defoamer;
8.Associated control:The method of changing the speed can improve the concentration of dissolv oxygen;The correlation control of feeding and pH; the correlation control feeding and dissolved oxygen.
9.Sterilization function:Manual control, the sterilization method includes jacket heating, and stea sterilization in the tank; or no steam in the tank, only relying on jacket heati
sterilization, sterilization temperature: 100-130 ℃;
10.Data display,recording and storage:The system has real-time display, data recording, data storage, data analy (histogram, curve).Line chart and Batch Report) output printing, password manageme exception analysis and alarm functions;
11.Setting and calibration:The parameters of each detection and control loop can be manually set and modified online on the screen, and the temperature, pH, DO2 sensors can be adjusted, and the flow rate of each peristaltic pump can be calibrated;
12.Diagnosis and protection:The system has the ability of self-adaptive and self diagnosis, and can automatically alarm and protect the abnormal situation according to the customer's settings.
13.Check the alarm accident:All alarm accidents can be recorded and consulted;
14.Password protection:The operation has password protection function, and the password is divided into operator and administrator level passwords;
15.Control switching:With automatic control and manual control switching.
Sterilization mode: in place sterilization, manual control.
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